12/13/2023 0 Comments Euthyroid sick syndrome![]() ![]() Speak to a GP or specialist if you're concerned that a medicine you're taking may be affecting your thyroid hormone levels. interferons – a class of medicine sometimes used to treat certain types of cancer and hepatitis C.amiodarone – a medicine sometimes used to treat an irregular heartbeat (arrhythmia).lithium – a medicine sometimes used to treat certain mental health conditions, including depression and bipolar disorder.Multiple mechanisms have been identified to contribute to the development of euthyroid sick syndrome, including alterations in the iodothyronine deiodinases, thyroid-stimulating hormone secretion, thyroid hormone binding. Therefore, damage to the pituitary gland may lead to an underactive thyroid.Īn underactive thyroid has also been linked to some viral infections or some medicines used to treat other conditions, such as: In this review, we discuss the characteristics, pathophysiology, and therapeutic implications of the euthyroid sick syndrome. The Great Ormond Street Hospital for Children has more information about congenital hypothyroidismĪ problem with the pituitary gland could lead to an underactive thyroid. The pituitary gland sits at the base of the brain and regulates the thyroid. It's usually picked up during routine screening soon after birth. This is called congenital hypothyroidism and is uncommon. However, iodine deficiency is uncommon in the UK.īabies are sometimes born with an underactive thyroid because the thyroid gland does not develop properly in the womb. Worldwide, a lack of dietary iodine is a common cause of an underactive thyroid, because the body needs iodine to make thyroxine. The condition is not considered to need treatment because there are no symptoms and the tests go back to normal when the stressful illness has passed. These treatments are sometimes used for an overactive thyroid (where the thyroid gland produces too much hormone) or thyroid cancer. Euthyroid Sick Syndrome is all about abnormal thyroid blood tests in patients without low thyroid symptoms. Previous thyroid treatmentĪn underactive thyroid can also occur as a side effect or complication of previous treatment to the thyroid gland, such as surgery or a treatment called radioactive iodine therapy. It's also common in people with another immune system disorder, such as type 1 diabetes and vitiligo. It's not clear what causes Hashimoto's disease, but it runs in families. This damages the thyroid, which means it's not able to make enough of the hormone thyroxine, leading to the symptoms of an underactive thyroid.Ī condition called Hashimoto's disease is the most common type of autoimmune reaction that causes an underactive thyroid. Immune systemĪn underactive thyroid often occurs when the immune system, which usually fights infection, attacks the thyroid gland. Most cases of an underactive thyroid are caused by the immune system attacking the thyroid gland and damaging it, or by damage that occurs as a result of treatments for thyroid cancer or an overactive thyroid. An underactive thyroid (hypothyroidism) is when your thyroid gland does not produce enough of the hormone thyroxine (also called T4). ![]()
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